Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies
نویسندگان
چکیده
منابع مشابه
Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies: model parameter considerations and consequences.
PURPOSE OF REVIEW Nonhuman primate (NHP) models of AIDS are powerful systems for evaluating HIV vaccine approaches in vivo. Authentic features of HIV-1 transmission, dissemination, target cell tropism, and pathogenesis, and aspects of anti-HIV-1 immune responses, can be recapitulated in NHPs provided the appropriate, specific model parameters are considered. Here, we discuss key model parameter...
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1 Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, 2 Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, 3 Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, 4 Department...
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ژورنال
عنوان ژورنال: Current Opinion in HIV and AIDS
سال: 2016
ISSN: 1746-630X
DOI: 10.1097/coh.0000000000000311